Hypersensitivity Pneumonitis

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Hypersensitivity pneumonitis / hypersensitivity pneumonitis (HP) or extrinsic allergic alveolitis is a group of lung diseases that are mediated by the immunological consequences of repeated exposure of the antigen is dispersed mainly by the particles when inhaled organic or low chemical bermolekul which further provoke hypersensitivity reaction with granulomatous inflammation in distal bronchioles and alveoli on sensitive subjects.
This disease is a result of the interaction between external antigen by the host immune system. This should be distinguished from inflammatory reactions such nonalergi inhalation fevers, toxic alveolitis and organic dust toxic syndrome is also associated with a result of inhalation of organic dust, but the reaction caused by a single exposure to high levels of organic dust levels and occur in those who have not previously been exposed. At this toxic reaction, sensitive individuals who get the same exposure will give the same clinical picture. Unlike the HP, only a small fraction of their exposure to the antigen is manifest as disease.
Hypersensitivity Pneumonitis is the primary key handling to avoid exposure to the antigen. Corticosteroids in acute HP provides a more rapid clinical improvement in lung function, but there was no significant difference in the long run out. Prednisone administered at a dose of 1 mg / kg / day or doses for 7-14 days equivalennya then lowered slowly for 2. 6 weeks. Educating the population at risk can help early recognition of symptoms and can be performed preventive efforts.