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PEDIATRIC CHRONIC COUGH LINKED TO REFLUX AND ALLERGIES
New research shows that chronic cough in children is most often caused by gastroesophageal reflux
and allergies. Researchers from Tulane University in New Orleans, LA, evaluated 40 patients aged 5 to
12 years with chronic cough (> 8 weeks in duration) with no obvious cause. Each patient underwent
extensive multispecialty testing. Results showed that reflux was the single most commonly associated
factor of chronic cough by itself (27.5 percent), followed by allergy (22.5 percent). All patients
received treatment for their underlying conditions, and all responded to their respective treatments.
This study is published in the September issue of CHEST, the peer-reviewed journal of the American
College of Chest Physicians.
STATINS MAY BENEFIT PATIENTS WITH COPD
Statins have been shown to benefit patients with cardiovascular disease and high cholesterol, but now
research shows that statins may provide significant benefits for patients with chronic obstructive
pulmonary disease (COPD). Researchers from the University of British Columbia reviewed data from
nine studies that illustrated the beneficial effects of statins on patients with COPD. Further analysis
showed that each study provided at least one benefit to patients with COPD, including reduced
exacerbations (3 studies); reduction in the number of COPD-related intubations and time to COPDrelated
intubations (1 study); improved pulmonary function (1 study); improved exercise capacity (1
study); improved mortality (2 studies); and improved all-cause mortality (3 studies). Researchers
conclude that, although statins show promise for patients with COPD, additional research is needed.
The article is published in the September issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.
PATIENTS WITH INTERSTITIAL LUNG DISEASE NEED NOT AVOID AIR TRAVEL
Patients with interstitial lung disease (ILD) are often concerned about the occurrence of pneumothorax
(collapsed lung) or other life-threatening events during air travel. However, new research shows that,
even in ILD with a high prevalence of spontaneous pneumothorax, such as lymphangioleiomyomatosis
(LAM), there is a relatively low risk of these events occurring. Researchers from the National
Institutes of Health reviewed records and imaging studies of 449 patients with sarcoidosis, idiopathic
pulmonary fibrosis, and LAM, who made a total of 816 trips by airplane and 416 trips by land. Results
showed that the frequency of pneumothorax in patients with LAM was 2.9 percent in those who
traveled by airplane and 1.3 percent in those who traveled by ground transportation. No patients with
IPF or sarcoidosis had a new pneumothorax while traveling. Researchers conclude that, in patients
with LAM, the presence of pneumothorax associated with air travel may be related to the high
incidence of pneumothorax from the disease itself and not to travel. This article is published in the
September issue of CHEST, the peer-reviewed journal of the American College of Chest Physicians.
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